Human Rights Watch using Drupal

The Human Rights Watch website uses Drupal to report on Human Rights, call people to action (support/donate/act), and inform the public. It makes strong use of Drupal's taxonomy system (categories), so you can view content by region and topic. Looks like the image manipulation is done using the Image Cache module.

The site is also available in many languages - just click the language link in the top right of the site to see it in action.

MothersClick

Part of the Parent'sClick network, the Mother'sClick website is a social networking site built on the Drupal platform, and providing a platform for mothers to interact through blog posts, forums, photos, discussions, recipes, reviews, classified ads, activities and more. Makes extensive use of Drupal's Organic Groups module, which allows mothers to create their own special interest groups which other mothers can join and interact through.

From the Mother'sClick website:

Amnesty International uses Open Source Drupal

News, information and call to action website

From the Amnesty International website: 

"Amnesty International is a worldwide movement of people who campaign for internationally recognized human rights to be respected and protected for everyone.

We believe human rights abuses anywhere are the concern of people everywhere.

So, outraged by human rights abuses but inspired by hope for a better world, we work to improve people’s lives through campaigning and international solidarity.